An infectious disease, especially of children, characterized by a sudden occurrence of fever, loss of appetite, and throat ulcerations, caused by a Coxsackie virus: Herpangina is also called mouth blisters and it is the name of a painful mouth infection caused by coxsackieviruses.

A medical-dictionary definition of herpangina state that it is an acute infectious disease caused by either group A or group B coxsackievirus, or by echoviruses, chiefly affecting young children in the summer.

Characteristics of herpangina include vesiculoulcerative lesions on the mucous membranes of the throat, dysphagia, vomiting, and fever.