megalo-, megal-, -megalia, -megaly

(Greek: large, big, very big)

acromegalogigantism (s) (noun) (no pl)
In pathology, a form of gigantism and acromegaly: Acromegalogigatism is due to a hypersecretion of the pituitary growth hormone beginning before puberty and continuing into maturity. It is characterized by an enlargement of the face and extremities.
acromegaloidism (s) (noun) (no pl)
A bodily condition resembling acromegaly but not due to pituitary disorder; pseudoacromegaly: Acromegaloidism can be triggered by a tumor in the lungs, in the pancreas, or in the adrenal glands.

It is often connected to an insulin resistance.

acromegaly (s) (noun), acromegalies (pl)
A chronic disease of adults caused by over secretion of the pituitary gland hormones and which is characterized by an enlargement of many parts of the bones of the extremities, such as the face, the nose, the ears, the jaws, the fingers, and the toes: The beginning of acromegaly is gradual and so neither the patient nor his or her family or friends notice it.

Early developments of acromegaly include muscular pains, headaches, and abnormal sweating. The teeth become separated, and the hands and feet gradually become bigger.

As acromegaly progresses, muscular weakness becomes a serious problem, and visual problems may progress into blindness.

adenomegaly (s) (noun), adenomegalies (pl)
Enlargement of one or both adrenal glands: Adenomegaly often occurs in the glands of the neck.
adrenomegaly (s) (noun) (no pl)
Enlargement of the adrenal glands: When Tom was examined by Dr. Tall, he was told that he had a case of adrenomegaly, or an increase of growth in his suprarenal glands.
Enlargement of blood vessels, causing swelling, especially of the eyelids.
atriomegaly (s), atriomegalies (pl) (nouns)
An abnormal enlargement of a chamber or part of the heart which may be one of the two smaller chambers of the heart or both of them (atria).

The atria consist of open spaces with recessed walls. The right atrium (space) receives deoxygenated blood from the body through the vena cava and pumps it down into the right ventricle which then sends it to the lungs and the left atrium receives oxygenated blood from the lungs and pumps it down into the left ventricle which delivers it to the body.

cheiromegaly, chiromegaly
1. Enlargement of one or both hands which may be seen in syringomyelia (condition characterized by the formation of a central fluid-containing cavity in the substance of the spinal cord).
2. Enlargement of the hands, wrists, or ankles.
Commonly seen as a congenital malformation or enlargement of the female genitals.
Abnormally large fingers or toes.
The inability to visualize correctly the size of objects.

They appear larger than they really are.

1. An abnormal enlargement of the liver; usually associated with liver disease or heart failure.
2. Etymology: hepato- comes from the Greek hepatikos, "of the liver" + megaly, from the Greek megas, "big, large" or "great" = "largeness of the liver".
1. An abnormal enlargement of the liver and the spleen.
2. Etymology: the word hepatosplenomegaly is compounded from the following Greek roots: hepato- from hepatikos, "of the liver" + spleno, from splen (the spleen) + megaly from megas, "big" or "great" = "large liver and spleen".

The spleen is an organ located in the upper left quadrant of the abdomen just below the diaphragm and protected under the lower left ribs.

1. An abnormal enlargement of the cell nucleus.
2. A slight, uniform increase in nuclear size in the cells of a tissue.

Related "big, large, great" words: grand-; macro-; magni-; major-; maxi-; mega-.