malaco-, malac-, malako-, -malacia +

(Greek: soft, softness; abnormal softening, soft-bodied)

onychomalacia
Abnormal softness of the finger and/or toe nails.
oophoromalacia
The softening of the ovary which is now considered to be an obsolete term.
ophthalmomalacia
Abnormal softening, or shrinkage, of the eyeball or eyeballs.
osteomalacia
A disease characterized by a gradual softening and bending of the bones with varying severity of pain.

Softening occurs because the bones contain osteoid tissue which has failed to calcify because of a lack of vitamin D or renal tubular dysfunction. It is more common in women than in men, osteomalacia often begins during pregnancy.

osteomalacic
A reference to osteomalacia which is a disease characterized by a gradual softening and bending of the bones with varying severity of pain.
phacomalacia
Softening of the lens, as may occur in hypermature cataract.
pneumomalacia
Softening of the lung tissue.
polioencephalomalacia
A neurologic disease of ruminant animals deficient in thiamin. Edema and softening and necrosis of the gray substance of the cerebral cortex are the primary manifestations.
retinomalacia
Softening of the retina.
scleromalacia
Degenerative thinning of the sclera, occurring in persons with rheumatoid arthritis and other collagen disorders.
splenomalacia
Softening of the spleen.
splenomyelomalacia
Pathologic softening of the spleen and bone marrow.
spondylomalacia
Softening of vertebrae with multiple collapsed vertebral bodies.
stomatomalacia
Pathologic softening of any of the structures of the mouth.
tarsomalacia
Softening of the tarsal cartilages of the eyelids.