malaco-, malac-, malako-, -malacia +
(Greek: soft, softness; abnormal softening, soft-bodied)
2. A softening of the spleen.
2. Morbid softening of a tissue or part.
3. Malacia denotes a morbid craving for certain articles of food or articles which are not devoid of nutrition, whereas pica denotes a desire for unnutritious substances; as in pregnancy or eating dirt.
2. A soft-skinned animal; an animal of any of the various groups called Malacodermata.
2. A form of chronic inflammation principally involving the urinary bladder and characterized by soft, pale, or yellow plaques on its mucosa.
The plaques are composed of macrophages and lymphocytes and an occasional multinucleated giant cell.
Mineralized, laminated concretions (Michaelis Gutmann bodies) and altered bacteria may be present within the macrophages. A localized defect in macrophage function or an abnormal response to coliform bacteria is believed to be the cause.