(Greek: highest point; prime, best time)
2. In medicine, the crisis or critical stage of a disease: After putting off going to her doctor, Janice finally decided to see him and the results of the tests indicated that her affliction was at its acme; and so, the doctor suggested that she wait until after her recovery before she attempted to go back to work.
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Eliza winced as if she were experiencing acmesthesia even before the doctor gave her an injection.
2. Localized skin inflammation as a result of over activity of the oil glands at the base of hair follicles.
Acne happens when oil (sebaceous) glands come to life around puberty, when these glands are stimulated by male hormones that are produced in the adrenal glands of both boys and girls.
The oil glands, which are located just beneath the skin, continuously produce and secrete oil through openings in the skin. The oil lubricates and protects the skin.
Under certain circumstances, cells that are close to the openings of the oil glands block the openings. This causes a buildup of oil underneath the skin.
Certain bacteria feast on this oil, multiply, and cause the surrounding tissues to become inflamed.
If the inflammation is near the surface, a person will get a pustule; if it's deeper, a papule (pimple); deeper still and it is termed a cyst.
If the oil breaks though to the surface, the result is a "whitehead". If the oil becomes oxidized (that is, acted on by oxygen in the air), the oil changes from white to black, and the result is a "blackhead".
2. A small needlelike structure or part; such as, one of the silicate or calcium carbonate processes supporting the soft tissue of certain invertebrates, especially sponges.