You searched for: “trichothiodystrophy
1. An abnormality of the hair shaft in which the fine, brittle hairs show alternating light and dark zones when viewed under a polarizing microscope.

The sulfur content of the hair is greatly reduced and mental retardation has frequently been a related feature.

2. Congenital fragile hair with multiple fractures resulting from low sulfur-containing amino acid, cysteine, content of the hair, mental impairment, and short stature.