1. A refusal to accept something: Little Susi put up a lot of resistance when told she should put on her pyjamas and go to bed!
2. Opposition offered by one force to another: The aggressive mob presented no resistance to the police officers when asked to disperse.
3. Immunity of a person's body toward diseases and germs: Somehow Tom showed good resistance in getting the flu like everybody else in his family.
4. The force that decelerates a moving vehicle or object: Most cars are made to lessen wind resistance by being very smooth and without any sharp hinderances.
5. The absence of responsiveness to an insecticide, drug, etc.: Some plants and insects have shown resistance to certain chemicals caused by continued exposure or genetic variation or mutation.