1. In psychiatry, a person who is suffering with the mental delusion of persecution and hatred: Jake decided to see a doctor because he had a feeling that his supervisor despised him and wanted to control his work more than his colleagues’, although his co-workers tried to convince him of the opposite; so, he thought he must have the symptoms of a misomaniac!
2. Someone who hates everyone and everything: As a child, Jeremy grew up in a difficult family situation and felt that his parents were always against him, no matter what he did; so, he had a real grudge and bitterness towards them and, as a result, his psychologist said he probably has become a misomaniac.