You searched for: “haemoglobinopathy
hemoglobinopathy, haemoglobinopathy
1. A blood disorder; such as, sickle-cell anemia, which is caused by a genetically determined change in the molecular structure of hemoglobin.
2. Disorder due to abnormalities in the hemoglobin molecule, the best known being sickle cell anemia in which there is a single amino acid substitution (valine for glutamate) in position six of the beta chain. In other cases one of the globin chains is synthesised at a slower rate, despite being normal in structure.