Before c, f, g, l, n, p, q, r, s, and t; ad- is changed to ac-, af-, ag-, al-, an-, ap-, aq-, ar-, as-, and at-.
In other words, the d of ad usually changes into the same letter as the first letter of the following root or word when it is a consonant: ad-fix becomes affix, and ad-sign becomes assign; therefore, making a double consonant.
Another example includes: attract as with ad-tract (drawn towards); so it has a double t. On the other hand when ad- precedes a vowel, as with adapt, it is simply ad-apt, with one d. For the same reason, there is only one d in adore and adumbrate, because ad- has combined with orare and umbra each of which starts with a vowel.
So, remember: since these Latin words begin with vowels and not consonants, the d of ad does not double as shown in the previous examples.
Used in medical prescriptions instructions.