1. To cause something to be unable to work in the normal way: "The technician had to disable the computer program before we could proceed adding more information to our blog."
2. Something that makes a person unable to do what was previously a normal part of life: "His father was disabled by the auto accident."
3. To prevent a device or system from working by disconnecting a part of it: "His friend was disabling the fire alarm because it was going off every so often for no valid reason."