1. To put an end to a customary, or enforced, separation of ethnic or racial groups based on gender in a place or institution; for example, in a workplace or a school: The members of the union of school janitors voted to desegregate their union and to welcome women as equal members.
2. To admit affiliates of all races or ethnic groups equally; especially, by force of law: The Civil Rights movement in the United States made significant gains when it was able to desegregate many schools, lunch counters, etc.