1. An ailment or indisposition caused by an excessive gobbling of digestible meals and intoxicants: Thomas decided to go to the doctor and find out why he suffered from crapulence because his wife and children were suffering from this severe malady.
2. A negative result when intemperance causes physical misery as a result of a lack of restraint when devouring edibles and inebriating drinks: Shirley denied suffering from intoxication, or crapulence, which her neighbor mentioned a few times when they were together, and she tried to cover up the truth by telling falsehoods and not revealing much about her personal habits.