Any pathological condition of the cranial bones: Craniopathy is a diffuse abnormality of the skull, especially one that is related to q metabolic (change in body form) disease.

Encephalopathy characterized by memory loss, vertigo, and generalized weakness: Metabolic craniopathy is due to a metabolic brain disease including hypoxia (abnormal oxygen reduction), ischemia (low oxygen condition because of inadequate blood flow), hypoglycaemia (abnormally diminished concentration of glucose in the blood), or secondary to another organ failure, such as the liver or kidney.