An inherited disorder causing abnormalities of the skull, the face, and the hands and feet: In acrocephalosyndactyly, there is closure too-early of some of the sutures of the skull (craniosynostosis).

This acrocephalosyndactyly results in an abnormally shaped head, which is unusually tall and peaked, and an abnormally shaped face with shallow eye sockets and underdevelopment of the midface. There is also a fusion of fingers and toes (syndactyly) and the broad ends of the thumbs and big toes.