An inherited disorder that includes abnormalities of the skull, face, hands, and feet: A person's acrocephalopolysyndactylism starts with the closure of some sutures of the skull and results in a tall peaked head, shallow eye sockets, and undeveloped cheekbones.

The development of acrocephalopolysyndactylism also results in fingers and toes that are fused, and the thumbs and the big toes have overly broad ends.