crin-, crino- (secrete) +
(Greek: to secrete, to exude; such as, a certain gland or glands)
Turner's syndrome (endocrine disorder), gonadal dysgenesis
1. A congenital condition of females associated with a defect or absence of an X-chromosome, characterized by short stature, sexual underdevelopment, and other physical abnormalities.
2. A genetic disorder affecting women in which only one X-chromosome per cell is present, instead of two, resulting in underdeveloped ovaries and underdevelopment of the womb, vagina, and breasts.
2. A genetic disorder affecting women in which only one X-chromosome per cell is present, instead of two, resulting in underdeveloped ovaries and underdevelopment of the womb, vagina, and breasts.
Named after Henry Hubert Turner (1892–1970), an American endocrinologist; this congenital endocrine disorder, or ovarian dysgenesis, is caused by the failure of the ovaries to respond to pituitary hormone stimulation.
Clinically, a female with this endocrine disorder has a shorter than normal stature; absence of secondary sexual characteristics, with infantile development of the vagina, uterus, and breast; failure to develop sexual maturation, webbing of the neck, and inconsistent cardiac defects.
