The regulation and control of temperature, specifically internal body temperature: Thermoregulation is the control of heat production and heat loss and specifically the maintenance of body temperature through physiological mechanisms activated by the hypothalamus (a neural control center at the base of the brain concerned with hunger, thirst, and other autonomic functions).

Thermoregulation concerns the various physiological processes by which the body regulates its internal temperature.

Thermoregulation is the process by which an organism regulates its internal body temperature which takes place by means of various physiological processes but can also involve behavior, such as moving away from a condition of extreme heat or cold.

The two most common forms are ectothermic and endothermic regulation.