1. To cause severe or widespread damage to something: The city has been devastated by the floods and hurricanes that have been going on this year.
2. To destroy; to render desolate: The Romans devastated the Greek city.
3. To overwhelm or to overpower people by greatly shocking or upsetting them: The shocking news of the murder was devastating the children who had held onto the hope that their father would still be alive.
4. To cause a person to feel extreme emotional pain and agony: Shirley was devastated by the breakup of her marriage.

Relating to the cause of great damage or harm: Ebola virus is a severe and devastating disease that consists of internal bleeding and very high fevers which is usually fatal for many people who live mostly in some African countries.