1. To arouse hostility or indifference in where there had formerly been love, affection, or friendliness.
2. To cause someone to change his or her previously friendly or supportive attitude and become unfriendly, unsympathetic, or hostile.
3. To make someone feel that he or she does not belong to or to share in something, or is isolated from it: "People with such behavior often feel alienated from society."
4. To cause something, especially someone's affections, to be directed toward somebody or something else.
5. To transfer (property or a right) to the ownership of another person; especially, by an act of the owner rather than by inheritance.